NTP Developmental and Reproductive Toxicity Technical Report on the Prenatal Development Studies of 2 ((1 (4 Phenoxyphenoxy)propan 2 yl)oxy)pyridine (CASRN 95737-68-1) in Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and New Zealand White (Hra:NZW SPF) Rabbits
| Document, Report, or Other Product Information | |
| Title: | NTP Developmental and Reproductive Toxicity Technical Report on the Prenatal Development Studies of 2 ((1 (4 Phenoxyphenoxy)propan 2 yl)oxy)pyridine (CASRN 95737-68-1) in Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and New Zealand White (Hra:NZW SPF) Rabbits |
| Subject: | These studies examined the potential for prenatal exposure to 2 ((1 (4 Phenoxyphenoxy)propan 2 yl)oxy)pyridine (MPEP) via gavage administration from implantation to just prior to birth to induce developmental alterations in the fetus. In parallel, MPEP was assessed in zebrafish to characterize the potential for MPEP to induce alterations in a non-mammalian alternative model. |
| Purpose (e.g., abstract): | This peer review done via letter will be conducted in Q2 2021. It will assess of the draft NTP developmental and reproductive toxicity technical report (DART-07). Information for the review will be posted once dates are finalized. |
| ISI or HISA: | No |
| Link to Information Product: | |
| IC: | NIEHS |
| IC Division, Office, or Program: | Division of the National Toxicology Program |
| NIH Contact: | Sheena Scruggs (984) 287 - 3355 sheena.scruggs@nih.gov |
| Review Description: | External scientists will peer review the draft report via letter. |
| Date of Review: | 2021-05-01 |
| Reviewer Names and Expertise | |
| Number of Reviewers: | 2-3 |
| Reviewer Nominations Requested? | |
| Upcoming Panels, Events: | View Upcoming Panels, Events, Notices, Meeting Updates |
| Technical/Draft Reports, Public Comments and Presentations: | https://ntp.niehs.nih.gov/events/panels/index.cfm |
| Past Roster, Notices, Meeting UPdates: | View Past Roster, Notices, Meeting Updates |
| Reviewer Expertise: | pathology, general tox, reproductive/developmental biology |
| How Selected: | NTP selected from identified experts |
| Opportunity for Public Comment? | Yes |