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NTP Technical Report on the Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophenone (CAS No. 131-57-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats

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Title: NTP Technical Report on the Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophenone (CAS No. 131-57-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats
Subject: NTP assessed the potential of continual exposure to 2-hydroxy-4-methoxybenzophenone (2H4MBP) via the diet to induce developmental toxicity, affect reproductive performance (e.g., pregnancy rate, litter size), and alter endocrine-sensitive endpoints, and included histopathological examination of the adult F1 male and female reproductive tracts.
Purpose (e.g., abstract): This peer review done via letter will be conducted in Q2 2021. It will assess of the draft NTP developmental and reproductive toxicity technical report (DART-05). Information for the review will be posted once dates are finalized.
ISI or HISA: No
Link to Information Product:
IC: NIEHS
IC Division, Office, or Program: Division of the National Toxicology Program
NIH Contact: Sheena Scruggs
(984) 287 - 3355
sheena.scruggs@nih.gov
Review Description: External scientists will peer review the draft report via letter.
Date of Review: 2021-05-01
Reviewer Names and Expertise
Number of Reviewers: 2-3
Reviewer Nominations Requested?
Upcoming Panels, Events: View Upcoming Panels, Events, Notices, Meeting Updates
Technical/Draft Reports, Public Comments and Presentations: https://ntp.niehs.nih.gov/events/panels/index.cfm
Past Roster, Notices, Meeting UPdates: View Past Roster, Notices, Meeting Updates
Reviewer Expertise: pathology, general tox, reproductive/developmental biology
How Selected: NTP selected from identified experts
Opportunity for Public Comment? Yes